In addition to cell type-specific marker analysis, each produced lot is tested for growth performance through multiple passages up to 15 population doublings (PD) under culture conditions without antibiotics and antimycotics.
SENTE DERMAL REPAIR SKIN
Information on donor hair and skin color is available for each lot. Our Human Follicle Dermal Papilla Cells are isolated mainly from normal human dermis of the lateral scalp. Since these cells express androgen receptors, they represent a well-suited model system for androgen-related research. Embedded in a laminin and collagen IV rich extracellular matrix, they are essential for induction and maintenance of hair growth. Human follicle dermal papilla cells are located in the dermal papilla at the base of hair follicles. Primary Normal Human Dermal Fibroblasts (NHDF) are isolated form the dermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs. Fibroblastsįibroblasts are morphologically heterogeneous with diverse appearances depending on their location in the body and their activity. Therefore, we recommend using cells isolated in Melanocyte Growth Medium M2 and also using this medium for cultivation. Since PMA is a tumor promoting mitogen, it can interfere with experimental approaches. Our melanocytes are isolated using either the serum-free, PMA (Phorbol Myristate Acetate)-containing Melanocyte Growth Medium or the serum-free and PMA-free Melanocyte Growth Medium M2. Our Normal Human Epidermal Melanocytes are isolated from the epidermis of juvenile foreskin or adult skin from different locations including the face, the breasts, the abdomen, and the thighs. About 5-10 % of the cells in the epidermis are melanocytes. Melanocytes are located in the stratum basale, but branch out between the keratinocytes in suprabasal layers. Additional donor information, like age, sex and skin pigmentation is available for each produced lot. They are the major cell type in the epidermis, making up about 90% of the cells. Primary Normal Human Epidermal Keratinocytes are available from single or from pooled donors isolated from the epidermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs.
We offer a comprehensive portfolio of primary human dermal cells including keratinocytes, melanocytes, fibroblasts and hair follicle cells to support these research applications. The in vitro culture of human skin cells is an essential research tool widely used for assaying dermal toxicity, pharmacological testing, and tissue repair. Cell-based Manufacturing Media Platform.Senté products are available through its exclusive network of physicians and medically supervised spas and on its website at For more information regarding Senté or to sell and recommend Senté products in your practice, contact us at. Founded in 2007 and based in San Diego, California, further information may be found at. Senté is a leader in the development of innovative skincare products based on patented glycosaminoglycan analog technologies. Senté is a privately held specialty dermatology company dedicated to delivering novel science-based skin care products targeting a range of skin discoloration conditions. In my evaluation, skin definitely looks more hydrated and has less crinkling and the skin surely feels smoother and less dry."
SENTE DERMAL REPAIR TRIAL
"We are excited to extend the benefits of Dermal Repair Cream to the entire body by expanding upon our Dermal Repair Cream franchise, to give customers the deep hydration and visible improvements they expect from Senté", said Laurent Combredet, CEO.ĭenver, CO area Dermatologist Joel Cohen, MD, FAAD, conducted a pre-launch case study and adds "We have had very positive feedback from our patients in the clinical trial regarding skin texture, firming and hydration.
SENTE DERMAL REPAIR SERIES
In a clinical case series conducted by leading Dermatologists, 100% of subjects showed improvement in dryness and 67% of subjects showed improvement in tactile roughness by week 8. The result is visibly smoother, more toned-looking skin. Engineered with patented HSA Technology formulated by a team of scientists and dermatologists, Dermal Repair Cream works to hydrate the skin and help reduce the. This deeply nourishing, repairing cream delivers lasting moisturization and promotes repair from within by boosting the skin's immune response to inflammation. The result is visibly smoother, more toned-looking skinĭermal Repair Body Cream extends the flagship Dermal Repair product line with a unique formula that combines Heparan Sulfate Analog (HSA) and lipids to mimic and support the skin barrier. This deeply nourishing, repairing cream delivers lasting moisturization and promotes repair from within by boosting the skins immune response to inflammation. Sente Dermal Repair Body Cream consumer brochure.
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